Antonio Maria Gasparo Sacchini (14 June 1730 – 6 October 1786) was an Italian opera composer.

Sacchini was born in Florence, but was raised in Naples, where he received his musical education at the San Onofrio conservatory. He wrote his first operas in Naples, thereafter moving to Venice, then London and eventually Paris, where he died. He was one of the leading composers of opera seria.

Sacchini's death at the age of 56 was attributed by some to depression and self-starvation following the loss of the patronage of Queen Marie Antoinette of France.